Extracellular motility and cell-to-cell transmission of enterohemorrhagic E. coli is driven by EspFU-mediated actin assembly.

Enteropathogenic and enterohemorrhagic Escherichia coli (EPEC and EHEC) are closely-related pathogens that attach tightly to intestinal epithelial cells, efface microvilli, and promote cytoskeletal rearrangements into protrusions called actin pedestals. To trigger pedestal formation, EPEC employs th...

Full description

Bibliographic Details
Main Authors: Katrina B Velle, Kenneth G Campellone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5557606?pdf=render