Trends and Challenges in Tumor Anti-Angiogenic Therapies

Excessive abnormal angiogenesis plays a pivotal role in tumor progression and is a hallmark of solid tumors. This process is driven by an imbalance between pro- and anti-angiogenic factors dominated by the tissue hypoxia-triggered overproduction of vascular endothelial growth factor (VEGF). VEGF-med...

Full description

Bibliographic Details
Main Authors: József Jászai, Mirko H.H. Schmidt
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/9/1102