Osteogenic Differentiation of Renal Interstitial Fibroblasts Promoted by lncRNA MALAT1 May Partially Contribute to Randall’s Plaque Formation

Osteogenic Differentiation of Renal Interstitial Fibroblasts Promoted by lncRNA MALAT1 May Partially Contribute to Randall’s Plaque Formation

BackgroundThe current belief is that Randall’s plaques (RP) constitute a nidus for the formation of idiopathic calcium oxalate stones, but the upstream events in RP formation remain unclear. The present study aimed to investigate whether RP formation shares similarities with biomineralization and to...

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Bibliographic Details
Main Authors: Zewu Zhu, Fang Huang, Weiping Xia, Huimin Zeng, Meng Gao, Yongchao Li, Feng Zeng, Cheng He, Jinbo Chen, Zhiyong Chen, Yang Li, Yu Cui, Hequn Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Randall’s plaque
MALAT1
Runx2
osteogenic differentiation
renal interstitial fibroblasts
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.596363/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.596363/full

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