Host kinase activity is required for Coxiella burnetii parasitophorous vacuole formation

Host kinase activity is required for Coxiella burnetii parasitophorous vacuole formation

Coxiella burnetii is the etiologic agent of human Q fever and targets alveolar phagocytic cells in vivo wherein the pathogen generates a phagolysosome-like parasitophorous vacuole (PV) for replication. C. burnetii displays a prolonged growth cycle, making PV maintenance critical for bacterial survi...

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Bibliographic Details
Main Authors: S. Kauser eHussain, Laura J Broederdorf, Uma M Sharma, Daniel E Voth
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Coxiella burnetii
Phosphorylation
pathogen
signaling
kinase
vacuole
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2010.00137/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2010.00137/full

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