B Cell Activating Factor (BAFF) Is Required for the Development of Intra-Renal Tertiary Lymphoid Organs in Experimental Kidney Transplantation in Rats

B Cell Activating Factor (BAFF) Is Required for the Development of Intra-Renal Tertiary Lymphoid Organs in Experimental Kidney Transplantation in Rats

Intra-renal tertiary lymphoid organs (TLOs) are associated with worsened outcome in kidney transplantation (Ktx). We used an anti-BAFF (B cell activating factor) intervention to investigate whether BAFF is required for TLO formation in a full MHC-mismatch Ktx model in rats. Rats received either ther...

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Bibliographic Details
Main Authors: Louisa Steines, Helen Poth, Marlene Herrmann, Antonia Schuster, Bernhard Banas, Tobias Bergler
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
tertiary lymphoid organs
kidney transplantation
B cells
BAFF
Online Access:https://www.mdpi.com/1422-0067/21/21/8045

Internet

https://www.mdpi.com/1422-0067/21/21/8045

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