Optimal number of spacers in CRISPR arrays.

Prokaryotic organisms survive under constant pressure of viruses. CRISPR-Cas system provides its prokaryotic host with an adaptive immune defense against viruses that have been previously encountered. It consists of two components: Cas-proteins that cleave the foreign DNA and CRISPR array that suits...

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Bibliographic Details
Main Authors: Alexander Martynov, Konstantin Severinov, Iaroslav Ispolatov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5749868?pdf=render