Optimal number of spacers in CRISPR arrays.
Prokaryotic organisms survive under constant pressure of viruses. CRISPR-Cas system provides its prokaryotic host with an adaptive immune defense against viruses that have been previously encountered. It consists of two components: Cas-proteins that cleave the foreign DNA and CRISPR array that suits...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-12-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC5749868?pdf=render |