SNPs in bone-related miRNAs are associated with the osteoporotic phenotype

Abstract Biogenesis and function of microRNAs can be influenced by genetic variants in the pri-miRNA sequences leading to phenotypic variability. This study aims to identify single nucleotide polymorphisms (SNPs) affecting the expression levels of bone-related mature microRNAs and thus, triggering a...

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Bibliographic Details
Main Authors: Laura De-Ugarte, Enrique Caro-Molina, Maria Rodríguez-Sanz, Miguel Angel García-Pérez, José M. Olmos, Manuel Sosa-Henríquez, Ramón Pérez-Cano, Carlos Gómez-Alonso, Luis Del Rio, Jesús Mateo-Agudo, José Antonio Blázquez-Cabrera, Jesús González-Macías, Javier del Pino-Montes, Manuel Muñoz-Torres, Manuel Diaz-Curiel, Jorge Malouf, Antonio Cano, José Luis Pérez-Castrillon, Xavier Nogues, Natalia Garcia-Giralt, Adolfo Diez-Perez
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00641-7