RAGE Silencing Ameliorates Neuroinflammation by Inhibition of p38-NF-κB Signaling Pathway in Mouse Model of Parkinson’s Disease

RAGE Silencing Ameliorates Neuroinflammation by Inhibition of p38-NF-κB Signaling Pathway in Mouse Model of Parkinson’s Disease

Accumulating evidence suggested that neuroinflammation played a crucial role in dopaminergic neuronal death in Parkinson’s disease (PD). The receptor for advanced glycation end products (RAGE), a multi-ligand receptor of the immunoglobulin superfamily, has been proposed as a key molecule in the onse...

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Bibliographic Details
Main Authors: Xiaoli Wang, Xiaoxuan Sun, Mengyue Niu, Xiaona Zhang, Jing Wang, Chang Zhou, Anmu Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Neuroscience
Subjects:
PD
neuroinflammation
RAGE
NF-κB
p38MAPK
COX-2
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00353/full

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https://www.frontiersin.org/article/10.3389/fnins.2020.00353/full

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