Cognitive Impairment in the 3xTg-AD Mouse Model of Alzheimer’s Disease is Affected by Aβ-ImmunoTherapy and Cognitive Stimulation

Clinical symptoms of Alzheimer’s Disease (AD) include behavioral alterations and cognitive impairment. These functional phenotypes early occur in triple-transgenic (3xTg-AD) mice. Specifically, behavioral alterations are first detected when mice are at around 2.5 months old and cognitive impairment...

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Bibliographic Details
Main Authors: Alejandro R. Roda, Gisela Esquerda-Canals, Joaquim Martí-Clúa, Sandra Villegas
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Pharmaceutics
Subjects:
tau
Online Access:https://www.mdpi.com/1999-4923/12/10/944