Metformin Improves Diabetic Bone Health by Re-Balancing Catabolism and Nitrogen Disposal.

Metformin, a leading drug used to treat diabetic patients, is reported to benefit bone homeostasis under hyperglycemia in animal models. However, both the molecular targets and the biological pathways affected by metformin in bone are not well identified or characterized. The objective of this study...

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Bibliographic Details
Main Authors: Xiyan Li, Yuqi Guo, Wenbo Yan, Michael P Snyder, Xin Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4696809?pdf=render