Rituximab Administration in Third Trimester of Pregnancy Suppresses Neonatal B-Cell Development

We describe the effect on the neonate of administration of rituximab to a woman with idiopathic thrombocytopenic purpura (ITP). Rituximab, an anti-CD20 antibody, was given weekly for 4 weeks to a woman with ITP in her third trimester of pregnancy. One month after the last rituximab administration a...

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Bibliographic Details
Main Authors: D. T. Klink, R. M. van Elburg, M. W. J. Schreurs, G. T. J. van Well
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2008/271363