Effect of donepezil hydrochloride on reference and working memory impairment after bilateral electrical lesion of nucleus basalis magnocellularis in rats model of Alzheimer disease

Background and Objective: Dysfunction and loss of basal forebrain cholinergic neurons and their cortical projections are the earliest pathological events in the pathogenesis of alzheimer disease (AD). This study was done to evaluate the effect of donepezil hydrochloride on reference and working memo...

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Bibliographic Details
Main Authors: Azade Eskandary, Ahmad Ali Moazedi, Hossein Najaphzadevarzi, Mohamad Reza Akhond
Format: Article
Language:fas
Published: Golestan University of Medical Sciences 2018-03-01
Series:مجله دانشگاه علوم پزشکی گرگان
Subjects:
Rat
Online Access:http://goums.ac.ir/journal/browse.php?a_code=A-10-1-1025&slc_lang=en&sid=1