Ruthenium Chloride—Induced Oxidative Cyclization of Trans-Resveratrol to (±)-ε-Viniferin and Antimicrobial and Antibiofilm Activity Against Streptococcus pneumoniae

Ruthenium Chloride—Induced Oxidative Cyclization of Trans-Resveratrol to (±)-ε-Viniferin and Antimicrobial and Antibiofilm Activity Against Streptococcus pneumoniae

Polyphenol ε-viniferin (2) is a protective phytochemical found in several plant families. Here, we report a simple and effective method for the synthesis of (±)-ε-viniferin (2) as major product and (±)-(E)-ω-viniferin (3) as a minor product. Synthesized viniferin compounds and standard viniferin wer...

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Bibliographic Details
Main Authors: Mukesh Kumar Yadav, Karabasappa Mailar, Jagadeesh Nagarajappa Masagalli, Sung-Won Chae, Jae-Jun Song, Won Jun Choi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Pharmacology
Subjects:
ε-viniferin
antimicobacterial
antibiofilm
Streptococcus pneumoniae
cell membrane
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00890/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00890/full

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