Fungal Immunomodulatory Protein from <i>Nectria haematococca</i> Suppresses Growth of Human Lung Adenocarcinoma by Inhibiting the PI3K/Akt Pathway

Fungal Immunomodulatory Protein from <i>Nectria haematococca</i> Suppresses Growth of Human Lung Adenocarcinoma by Inhibiting the PI3K/Akt Pathway

Lung cancer is a common disease that is associated with poor prognosis. Fungal immunomodulatory protein from <i>Nectria haematococca</i> (FIP-nha) has potential as a lung cancer therapeutic; as such, illuminating its anti-tumor mechanism is expected to facilitate novel treatment options....

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Bibliographic Details
Main Authors: Yingying Xie, Shuying Li, Lei Sun, Shujun Liu, Fengzhong Wang, Boting Wen, Lichao Sun, Xiangdong Fang, Yushuang Chai, Hao Cao, Ning Jia, Tianyi Gu, Xiaomin Lou, Fengjiao Xin
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:International Journal of Molecular Sciences
Subjects:
fungal immunomodulatory protein
<i>Nectria haematococca</i>
lung adenocarcinoma
PI3K/Akt
apoptosis
autophagy
cell cycle arrest
Online Access:https://www.mdpi.com/1422-0067/19/11/3429

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https://www.mdpi.com/1422-0067/19/11/3429

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