Application of cryopreservation to tooth germ transplantation for root development and tooth eruption

Abstract We cryopreserved mouse tooth germs with widely open cervical margins of the enamel organ to overcome difficulties in cryoprotectant permeation and tested their efficacy by transplanting them into recipient mice. The upper right first molar germs of 8-day-old donor mice were extracted and ca...

Full description

Bibliographic Details
Main Authors: Xinghan Li, Megumi Nakamura, Weidong Tian, Yasuyuki Sasano
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88975-1