Preclinical Assessment of a 68Ga-DOTA-Functionalized Depsipeptide as a Radiodiagnostic Infection Imaging Agent

Preclinical Assessment of a 68Ga-DOTA-Functionalized Depsipeptide as a Radiodiagnostic Infection Imaging Agent

The study assessed a radiolabeled depsipeptide conjugate (68Ga-DOTA-TBIA101) for its potential as an imaging agent targeting infection or infection-associated inflammation. 68Ga-labeled DOTA-TBIA101 imaging was performed in (NZR1) healthy rabbits; (NZR2) rabbits bearing muscular sterile inflammation...

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Bibliographic Details
Main Authors: Thomas Ebenhan, Botshelo Brenda Mokaleng, Jacobus Daniel Venter, Hendrik Gert Kruger, Jan Rijn Zeevaart, Mike Sathekge
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Molecules
Subjects:
DOTA-TBIA101
depsipeptides
infection
inflammation
tuberculosis
68Ga/68Ge generator
PET/CT imaging
Online Access:https://www.mdpi.com/1420-3049/22/9/1403

Internet

https://www.mdpi.com/1420-3049/22/9/1403

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