Application of CRISPR-Cas9 gene editing for congenital heart disease

Clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9 (CRISPR-Cas9) is an ancient prokaryotic defense system that precisely cuts foreign genomic DNA under the control of a small number of guide RNAs. The CRISPR-Cas9 system facilitates efficient double-stranded DNA...

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Bibliographic Details
Main Authors: Heeyoung Seok, Rui Deng, Douglas B. Cowan, Da-Zhi Wang
Format: Article
Language:English
Published: The Korean Pediatric Society 2021-06-01
Series:Clinical and Experimental Pediatrics
Subjects:
Online Access:http://www.e-cep.org/upload/pdf/cep-2020-02096.pdf