Regulation of fatty acid trafficking in liver by thioesterase superfamily member 1

Thioesterase superfamily member 1 (Them1) is an acyl-CoA thioesterase that is highly expressed in brown adipose tissue, where it functions to suppress energy expenditure. Lower Them1 expression levels in the liver are upregulated in response to high-fat feeding. Them1−/− mice are resistant to diet-i...

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Bibliographic Details
Main Authors: Anal Desai, Michele Alves-Bezerra, Yingxia Li, Cafer Ozdemir, Curtis J. Bare, Yue Li, Susan J. Hagen, David E. Cohen
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520342395