Versatile Role of Rab27a in Glioma: Effects on Release of Extracellular Vesicles, Cell Viability, and Tumor Progression

Versatile Role of Rab27a in Glioma: Effects on Release of Extracellular Vesicles, Cell Viability, and Tumor Progression

Introduction: Glioma cells exert influence over the tumor-microenvironment in part through the release of extracellular vesicles (EVs), membrane-enclosed structures containing proteins, lipids, and RNAs. In this study, we evaluated the function of Ras-associated protein 27a (Rab27a) in glioma and ev...

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Bibliographic Details
Main Authors: Thomas S. van Solinge, Erik R. Abels, Lieke L. van de Haar, Killian S. Hanlon, Sybren L. N. Maas, Rosalie Schnoor, Jeroen de Vrij, Xandra O. Breakefield, Marike L. D. Broekman
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Molecular Biosciences
Subjects:
glioma
glioblastoma
extracellular vesicles
exosomes
tumor microenvironment
Rab27a
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2020.554649/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2020.554649/full

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