A family of helminth molecules that modulate innate cell responses via molecular mimicry of host antimicrobial peptides.

Over the last decade a significant number of studies have highlighted the central role of host antimicrobial (or defence) peptides in modulating the response of innate immune cells to pathogen-associated ligands. In humans, the most widely studied antimicrobial peptide is LL-37, a 37-residue peptide...

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Bibliographic Details
Main Authors: Mark W Robinson, Sheila Donnelly, Andrew T Hutchinson, Joyce To, Nicole L Taylor, Raymond S Norton, Matthew A Perugini, John P Dalton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21589904/pdf/?tool=EBI