Inhalable Fucoidan Microparticles Combining Two Antitubercular Drugs with Potential Application in Pulmonary Tuberculosis Therapy

Inhalable Fucoidan Microparticles Combining Two Antitubercular Drugs with Potential Application in Pulmonary Tuberculosis Therapy

The pulmonary delivery of antitubercular drugs is a promising approach to treat lung tuberculosis. This strategy not only allows targeting the infected organ instantly, it can also reduce the systemic adverse effects of the antibiotics. In light of that, this work aimed at producing fucoidan-based i...

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Bibliographic Details
Main Authors: Ludmylla Cunha, Susana Rodrigues, Ana M. Rosa da Costa, M Leonor Faleiro, Francesca Buttini, Ana Grenha
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Polymers
Subjects:
alveolar macrophages
fucoidan
isoniazid
inhalable microparticles
rifabutin
spray-drying
tuberculosis therapy
Online Access:http://www.mdpi.com/2073-4360/10/6/636

Internet

http://www.mdpi.com/2073-4360/10/6/636

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