Metabolomic study on idiosyncratic liver injury induced by different extracts of Polygonum multiflorum in rats integrated with pattern recognition and enriched pathways analysis

Metabolomic study on idiosyncratic liver injury induced by different extracts of Polygonum multiflorum in rats integrated with pattern recognition and enriched pathways analysis

Currently, numerous liver injury cases related to a famous Chinese herb- Polygonum Multiflorum (Heshouwu in Chinese) have attracted great attention in many countries. Our previous work showed that Heshouwu-induced hepatotoxicity belonged to idiosyncratic drug-induced liver injury (IDILI). Unfortunat...

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Bibliographic Details
Main Authors: Chun-yu Li, Can Tu, Dan Gao, Rui-lin Wang, Hai-zhu Zhang, Ming Niu, Rui-yu Li Li, Cong-En Zhang, Rui-sheng Li, Xiao-he Xiao, Mei-hua Yang, Jia-Bo Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Pharmacology
Subjects:
Metabolomics
Stilbenes
pathway analysis
Polygonum multiflorum
Idiosyncratic liver injury
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00483/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00483/full

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