Cellular vaccination of MLH1−/− mice – an immunotherapeutic proof of concept study

Cellular vaccination of MLH1−/− mice – an immunotherapeutic proof of concept study

Mismatch-repair deficiency (MMR-D) is closely linked to hypermutation and accordingly, high immunogenicity. MMR-D-related tumors thus constitute ideal vaccination targets for both therapeutic and prophylactic approaches. Herein, the prophylactic and therapeutic impact of a cellular vaccine on tumor...

Full description

Bibliographic Details
Main Authors: Claudia Maletzki, Yvonne Saara Gladbach, Mohamed Hamed, Georg Fuellen, Marie-Luise Semmler, Jan Stenzel, Michael Linnebacher
Format: Article
Language:English
Published: Taylor & Francis Group 2018-03-01
Series:OncoImmunology
Subjects:
cellular vaccine
mmr deficiency
in vivo imaging
tumor microenvironment
target gene identification
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1408748

Internet

http://dx.doi.org/10.1080/2162402X.2017.1408748

Similar Items