CRISPR/Cascade 9-Mediated Genome Editing-Challenges and Opportunities

CRISPR/Cascade 9-Mediated Genome Editing-Challenges and Opportunities

Clustered Regularly Interspaced Palindromic Repeats (CRISPR) and Cascade 9 (also known as Cas9, CRISPR associated protein 9) confer protection against invading viruses or plasmids. The CRISPR/Cascade 9 system constitutes one of the most powerful genome technologies available to researchers today. So...

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Bibliographic Details
Main Authors: Bhaskar Roy, Jing Zhao, Chao Yang, Wen Luo, Teng Xiong, Yong Li, Xiaodong Fang, Guanjun Gao, Chabungbam O. Singh, Lise Madsen, Yong Zhou, Karsten Kristiansen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Genetics
Subjects:
CRISPR
Cascade 9
genome editing
off-target effects
gene targeting
RNA guided system
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00240/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00240/full

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