Neurobehavioural, neuropathological and biochemical profiles in a novel mouse model of co-morbid posttraumatic stress disorder and mild traumatic brain injury.

Neurobehavioural, neuropathological and biochemical profiles in a novel mouse model of co-morbid posttraumatic stress disorder and mild traumatic brain injury.

Co-morbid mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD) has become the signature disorder for returning combat veterans. The clinical heterogeneity and overlapping symptomatology of mTBI and PTSD underscore the need to develop a preclinical model that will enable the c...

Full description

Bibliographic Details
Main Authors: Joseph Olubunmi Ojo, Marianne Banks Greenberg, Paige eLeary, Benoit eMouzon, Corbin eBachmeier, Michael eMullan, David M Diamond, Fiona eCrawford
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
posttraumatic stress disorder
Cognitive Function
mouse models
mild traumatic brain injury
anxiety and social behavior
plasma and brain biomarkers
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00213/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00213/full

Similar Items