Antiapoptotic signaling by a remyelination-promoting human antimyelin antibody

Antiapoptotic signaling by a remyelination-promoting human antimyelin antibody

Stabilizing the survival of oligodendrocytes and oligodendrocyte precursors within and near lesions in patients suffering from multiple sclerosis (MS) and other demyelinating diseases is an important therapeutic goal. Previous studies have identified a human-derived monoclonal IgM antibody designate...

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Bibliographic Details
Main Authors: Charles L Howe, Allan J Bieber, Arthur E Warrington, Larry R Pease, Moses Rodriguez
Format: Article
Language:English
Published: Elsevier 2004-02-01
Series:Neurobiology of Disease
Subjects:
Autoantibody
Glia
Multiple sclerosis
Apoptosis
Myelin
Demyelinating disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103001888

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http://www.sciencedirect.com/science/article/pii/S0969996103001888

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