Lycopene prevents lipid accumulation in hepatocytes by stimulating PPARα and improving mitochondrial function

Lycopene prevents lipid accumulation in hepatocytes by stimulating PPARα and improving mitochondrial function

The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased over the decades. Lycopene (LYC), a major carotenoid present in tomato, has been previously demonstrated to possess liver-protecting and lipid-lowering bioactivities. However, the underlying mechanism of how LYC impact on the l...

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Bibliographic Details
Main Authors: Jia Wang, Tonghui Geng, Qianhui Zou, Ningru Yang, Weiyang Zhao, Yitong Li, Xintong Tan, Tian Yuan, Xuebo Liu, Zhigang Liu
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Journal of Functional Foods
Subjects:
Lycopene
Lipid metabolism dysfunction
Mitochondrial function
Nonalcoholic fatty liver disease
PPARα
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464620300815

Internet

http://www.sciencedirect.com/science/article/pii/S1756464620300815

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