Occlusion of regulatory sequences by promoter nucleosomes in vivo.

Nucleosomes are believed to inhibit DNA binding by transcription factors. Theoretical attempts to understand the significance of nucleosomes in gene expression and regulation are based upon this assumption. However, nucleosomal inhibition of transcription factor binding to DNA is not complete. Rathe...

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Bibliographic Details
Main Authors: Changhui Mao, Christopher R Brown, Joachim Griesenbeck, Hinrich Boeger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3048331?pdf=render