Pharmacokinetic and Metabolic Characteristics of Herb-Derived Khellactone Derivatives, A Class of Anti-HIV and Anti-Hypertensive: A Review

Pharmacokinetic and Metabolic Characteristics of Herb-Derived Khellactone Derivatives, A Class of Anti-HIV and Anti-Hypertensive: A Review

A vast number of structural modifications have been performed for khellactone derivatives (KDs) that have been widely concerned owing to their diverse biological properties, including anti-hypertension, anti-HIV, reversing P-glycoprotein (P-gp) mediated multidrug resistance, and anti-inflammation ef...

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Bibliographic Details
Main Authors: Wanghui Jing, Ruilin Liu, Wei Du, Zhimin Luo, Pengqi Guo, Ting Zhang, Aiguo Zeng, Chun Chang, Qiang Fu
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Molecules
Subjects:
khellactone derivatives
metabolism
pharmacokinetics
structure-metabolism relationship
drug-drug interactions
drug development
Online Access:http://www.mdpi.com/1420-3049/21/3/314

Internet

http://www.mdpi.com/1420-3049/21/3/314

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