The apparent permeabilities of Caco-2 cells to marketed drugs: magnitude, and independence from both biophysical properties and endogenite similarities

We bring together fifteen, nonredundant, tabulated collections (amounting to 696 separate measurements) of the apparent permeability (Papp) of Caco-2 cells to marketed drugs. While in some cases there are some significant interlaboratory disparities, most are quite minor. Most drugs are not especial...

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Bibliographic Details
Main Authors: Steve O’Hagan, Douglas B. Kell
Format: Article
Language:English
Published: PeerJ Inc. 2015-11-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/1405.pdf