Non-alcoholic steatohepatitis-like pattern in liver biopsy of rheumatoid arthritis patients with persistent transaminitis during low-dose methotrexate treatment.

OBJECTIVE:The mechanism of liver injury with low-dose methotrexate (MTX) is incompletely understood. This study was designed to evaluate the association between non-alcoholic fatty liver disease (NAFLD) and liver injury during MTX treatment for rheumatoid arthritis (RA). METHODS:Between October 2014...

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Bibliographic Details
Main Authors: Shunsuke Mori, Nobuyuki Arima, Masahiro Ito, Shigetoshi Fujiyama, Yasuhiro Kamo, Yukitaka Ueki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6108522?pdf=render