The role of JMJD6/U2AF65/AR-V7 axis in castration-resistant prostate cancer progression
Abstract Castration-resistant prostate cancer (CRPC) remains prostate cancer research and treatment bottleneck. Abnormal androgen receptor (AR) activation still has a pivotal role in CRPC. Multiple mechanisms involve the process, of which overabundant AR-V7 mRNA splicing production is currently focu...
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| Format: | Article |
| Language: | English |
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BMC
2021-01-01
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| Series: | Cancer Cell International |
| Online Access: | https://doi.org/10.1186/s12935-020-01739-1 |