Functional Roles of Matrix Metalloproteinases and Their Inhibitors in Melanoma

The extracellular matrix (ECM) plays an important role in the regulation of the tissue microenvironment and in the maintenance of cellular homeostasis. Several proteins with a proteolytic activity toward several ECM components are involved in the regulation and remodeling of the ECM. Among these, Ma...

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Bibliographic Details
Main Authors: Salvatore Napoli, Chiara Scuderi, Giuseppe Gattuso, Virginia Di Bella, Saverio Candido, Maria Sofia Basile, Massimo Libra, Luca Falzone
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
ECM
OPN
Online Access:https://www.mdpi.com/2073-4409/9/5/1151