Severely impaired hippocampal neurogenesis associates with an early serotonergic deficit in a BAC α-synuclein transgenic rat model of Parkinson's disease

Severely impaired hippocampal neurogenesis associates with an early serotonergic deficit in a BAC α-synuclein transgenic rat model of Parkinson's disease

Parkinson's disease (PD) is a multisystem disorder, involving several monoaminergic neurotransmitter systems resulting in a broad range of motor and non-motor symptoms. Pathological hallmarks of PD are the loss of dopaminergic neurons and the accumulation of alpha-synuclein, however also being...

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Bibliographic Details
Main Authors: Zacharias Kohl, Nada Ben Abdallah, Jonathan Vogelgsang, Lucas Tischer, Janina Deusser, Davide Amato, Scott Anderson, Christian P. Müller, Olaf Riess, Eliezer Masliah, Silke Nuber, Jürgen Winkler
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
Alpha-synuclein
Hippocampus
5-HT
Neurogenesis
Dendritogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115300796

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http://www.sciencedirect.com/science/article/pii/S0969996115300796

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