The Differences in the Involvements of Loci of Promoter Region and Ile50Val in Interleukin-4 Receptor α Chain Gene between Atopic Dermatitis and Japanese Cedar Pollinosis

The Differences in the Involvements of Loci of Promoter Region and Ile50Val in Interleukin-4 Receptor α Chain Gene between Atopic Dermatitis and Japanese Cedar Pollinosis

Background: Atopic dermatitis (AD) and Japanese cedar pollinosis (JCP) are common chronically allergic diseases associated with the activation of T-helper 2 cells. Recent studies have shown that polymorphisms in the genes for IL-4 receptor α chain (IL4RA) may contribute to susceptibility of AD and J...

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Bibliographic Details
Main Authors: Takeshi Tanaka, Yoshiaki Hitomi, Yasuhiro Kambayashi, Yuri Hibino, Yuma Fukutomi, Aki Shibata, Naotoshi Sugimoto, Kotaro Hatta, Akira Eboshida, Tadashi Konoshita, Hiroyuki Nakamura
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Allergology International
Subjects:
atopic dermatitis
haplotype
IL-4
Japanese cedar pollinosis
polymorphism
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015301945

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http://www.sciencedirect.com/science/article/pii/S1323893015301945

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