Expression Profiling of Glioblastoma Cell Lines Reveals Novel Extracellular Matrix-Receptor Genes Correlated With the Responsiveness of Glioma Patients to Ionizing Radiation

Expression Profiling of Glioblastoma Cell Lines Reveals Novel Extracellular Matrix-Receptor Genes Correlated With the Responsiveness of Glioma Patients to Ionizing Radiation

Glioblastoma (GBM) is the most lethal and frequent type of brain tumor, leading patients to death in approximately 14 months after diagnosis. GBM treatment consists in surgical removal followed by radio and chemotherapy. However, tumors commonly relapse and the treatment promotes only a slight incre...

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Bibliographic Details
Main Authors: Rodolfo Bortolozo Serafim, Patrick da Silva, Cibele Cardoso, Luis Fernando Macedo Di Cristofaro, Renato Petitto Netto, Rodrigo de Almeida, Geovana Navegante, Camila Baldin Storti, Juliana Ferreira de Sousa, Felipe Canto de Souza, Rodrigo Panepucci, Cristiano Gallina Moreira, Larissa Siqueira Penna, Wilson Araujo Silva, Valeria Valente
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
glioblastoma
GBM cell lines
expression profiling
extracellular matrix
ECM-receptors
radioresistance
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.668090/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.668090/full

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