Exercise can rescue recognition memory impairment in a model with reduced adult hippocampal neurogenesis

Exercise can rescue recognition memory impairment in a model with reduced adult hippocampal neurogenesis

Running is a potent stimulator of cell proliferation in the adult dentate gyrus and these newly generated hippocampal neurons seem to be implicated in memory functions. Here we have used a mouse model expressing activated Ras under the direction of the neuronal Synapsin I promoter (named synRas mice...

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Bibliographic Details
Main Authors: Pauline Lafenetre, Oliver Leske, Zhanlu Ma-Högemeie, Aiden Haghikia, Zoe Bichler, Petra Wahle, Rolf Heumann
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-02-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Brain-Derived Neurotrophic Factor
adult neurogenesis
proliferation
TrkB
recognition memory
: exercise.
Online Access:http://journal.frontiersin.org/Journal/10.3389/neuro.08.034.2009/full

Internet

http://journal.frontiersin.org/Journal/10.3389/neuro.08.034.2009/full

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