Plasma metabolomic profiling suggests early indications for predisposition to latent insulin resistance in children conceived by ICSI.

BACKGROUND: There have been increasing indications about an epigenetically-based elevated predisposition of assisted reproductive technology (ART) offspring to insulin resistance, which can lead to an unfavorable cardio-metabolic profile in adult life. However, the relevant long-term systematic mole...

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Bibliographic Details
Main Authors: Alexandra Gkourogianni, Ioanna Kosteria, Aristeidis G Telonis, Alexandra Margeli, Emilia Mantzou, Maria Konsta, Dimitrios Loutradis, George Mastorakos, Ioannis Papassotiriou, Maria I Klapa, Christina Kanaka-Gantenbein, George P Chrousos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3984097?pdf=render