Tumors Widely Express Hundreds of Embryonic Germline Genes

We have recently described a class of 756 genes that are widely expressed in cancers, but are normally restricted to adult germ cells, referred to as germ cell cancer genes (GC genes). We hypothesized that carcinogenesis involves the reactivation of biomolecular processes and regulatory mechanisms t...

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Bibliographic Details
Main Authors: Jan Willem Bruggeman, Naoko Irie, Paul Lodder, Ans M. M. van Pelt, Jan Koster, Geert Hamer
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/12/3812