Effect of Tetrodotoxin Pellets in a Rat Model of Postherpetic Neuralgia

Effect of Tetrodotoxin Pellets in a Rat Model of Postherpetic Neuralgia

Postherpetic neuralgia (PHN) is nerve pain caused by a reactivation of the varicella zoster virus. Medications are used to reduce PHN but their use is limited by serious side effects. Tetrodotoxin (TTX) is a latent neurotoxin that can block neuropathic pain, but its therapeutic index is only 3–5 tim...

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Bibliographic Details
Main Authors: Bihong Hong, Jipeng Sun, Hongzhi Zheng, Qingqing Le, Changsen Wang, Kaikai Bai, Jianlin He, Huanghuang He, Yanming Dong
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Marine Drugs
Subjects:
postherpetic neuralgia
tetrodotoxin
TTX pellets
pharmacokinetics
varicella-zoster virus
Online Access:http://www.mdpi.com/1660-3397/16/6/195

Internet

http://www.mdpi.com/1660-3397/16/6/195

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