Notch Signaling Mediates Skeletal Muscle Atrophy in Cancer Cachexia Caused by Osteosarcoma

Skeletal muscle atrophy in cancer cachexia is mediated by the interaction between muscle stem cells and various tumor factors. Although Notch signaling has been known as a key regulator of both cancer development and muscle stem cell activity, the potential involvement of Notch signaling in cancer c...

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Bibliographic Details
Main Authors: Xiaodong Mu, Rashmi Agarwal, Daniel March, Adam Rothenberg, Clifford Voigt, Jessica Tebbets, Johnny Huard, Kurt Weiss
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Sarcoma
Online Access:http://dx.doi.org/10.1155/2016/3758162