Akt1 in osteoblasts and osteoclasts controls bone remodeling.

Bone mass and turnover are maintained by the coordinated balance between bone formation by osteoblasts and bone resorption by osteoclasts, under regulation of many systemic and local factors. Phosphoinositide-dependent serine-threonine protein kinase Akt is one of the key players in the signaling of...

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Bibliographic Details
Main Authors: Naohiro Kawamura, Fumitaka Kugimiya, Yasushi Oshima, Shinsuke Ohba, Toshiyuki Ikeda, Taku Saito, Yusuke Shinoda, Yosuke Kawasaki, Naoshi Ogata, Kazuto Hoshi, Toru Akiyama, William S Chen, Nissim Hay, Kazuyuki Tobe, Takashi Kadowaki, Yoshiaki Azuma, Sakae Tanaka, Kozo Nakamura, Ung-il Chung, Hiroshi Kawaguchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2020440?pdf=render