Adipose PTEN regulates adult adipose tissue homeostasis and redistribution via a PTEN-leptin-sympathetic loop

Objective: Despite the large body of work describing the tumor suppressor functions of Phosphatase and tensin homologue deleted on chromosome ten (PTEN), its roles in adipose homeostasis of adult animals are not yet fully understood. Here, we sought to determine the role of PTEN in whole-body adipos...

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Bibliographic Details
Main Authors: Wei Huang, Nicholas J. Queen, Travis B. McMurphy, Seemaab Ali, Lei Cao
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877819309111