QSAR Model for Predicting the Cannabinoid Receptor 1 Binding Affinity and Dependence Potential of Synthetic Cannabinoids

QSAR Model for Predicting the Cannabinoid Receptor 1 Binding Affinity and Dependence Potential of Synthetic Cannabinoids

In recent years, there have been frequent reports on the adverse effects of synthetic cannabinoid (SC) abuse. SCs cause psychoactive effects, similar to those caused by marijuana, by binding and activating cannabinoid receptor 1 (CB1R) in the central nervous system. The aim of this study was to esta...

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Bibliographic Details
Main Authors: Wonyoung Lee, So-Jung Park, Ji-Young Hwang, Kwang-Hyun Hur, Yong Sup Lee, Jongmin Kim, Xiaodi Zhao, Aekyung Park, Kyung Hoon Min, Choon-Gon Jang, Hyun-Ju Park
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Molecules
Subjects:
cannabinoid receptor 1
synthetic cannabinoids
quantitative structure-activity relationship
multiple linear regression
partial least squares regression
dependence and abuse potential
Online Access:https://www.mdpi.com/1420-3049/25/24/6057

Internet

https://www.mdpi.com/1420-3049/25/24/6057

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