Identification of roles for H264, H306, H439, and H635 in acid-dependent lipoprotein release by the LDL receptor
Lipoproteins internalized by the LDL receptor (LDLR) are released from this receptor in endosomes through a process that involves acid-dependent conformational changes in the receptor ectodomain. How acidic pH promotes this release process is not well understood. Here, we assessed roles for six hist...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-02-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520314176 |