Characterization of a stable, metronidazole-resistant Clostridium difficile clinical isolate.

BACKGROUND: Clostridium difficile are gram-positive, spore forming anaerobic bacteria that are the leading cause of healthcare-associated diarrhea, usually associated with antibiotic usage. Metronidazole is currently the first-line treatment for mild to moderate C. difficile diarrhea however recurre...

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Bibliographic Details
Main Authors: Tarah Lynch, Patrick Chong, Jason Zhang, Romeo Hizon, Tim Du, Morag R Graham, Daniel R Beniac, Timothy F Booth, Pamela Kibsey, Mark Miller, Denise Gravel, Michael R Mulvey, Canadian Nosocomial Infection Surveillance Program (CNISP)
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3547915?pdf=render