Immunological Pathogenesis of Membranous Nephropathy: Focus on PLA2R1 and Its Role

Membranous nephropathy (MN) is the major cause of nephrotic syndrome with special pathological features, caused by the formation of immune complexes in the space between podocytes and the glomerular basement membrane. In idiopathic membranous nephropathy (IMN) the immune complexes are formed by circ...

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Bibliographic Details
Main Authors: Wenbin Liu, Chang Gao, Haoran Dai, Yang Zheng, Zhaocheng Dong, Yu Gao, Fei Liu, Zihan Zhang, Zhiyuan Liu, Weijing Liu, Baoli Liu, Qingquan Liu, Jialan Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01809/full