The Candida albicans biofilm gene circuit modulated at the chromatin level by a recent molecular histone innovation.

Histone H3 and its variants regulate gene expression but the latter are absent in most ascomycetous fungi. Here, we report the identification of a variant histone H3, which we have designated H3VCTG because of its exclusive presence in the CTG clade of ascomycetes, including Candida albicans, a huma...

Full description

Bibliographic Details
Main Authors: Laxmi Shanker Rai, Rima Singha, Hiram Sanchez, Tanmoy Chakraborty, Bipin Chand, Sophie Bachellier-Bassi, Shantanu Chowdhury, Christophe d'Enfert, David R Andes, Kaustuv Sanyal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-08-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000422