Improving predictions of protein-protein interfaces by combining amino acid-specific classifiers based on structural and physicochemical descriptors with their weighted neighbor averages.

Protein-protein interactions are involved in nearly all regulatory processes in the cell and are considered one of the most important issues in molecular biology and pharmaceutical sciences but are still not fully understood. Structural and computational biology contributed greatly to the elucidatio...

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Bibliographic Details
Main Authors: Fábio R de Moraes, Izabella A P Neshich, Ivan Mazoni, Inácio H Yano, José G C Pereira, José A Salim, José G Jardine, Goran Neshich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3904977?pdf=render