Neuroinflammation in the pathogenesis of Alzheimer´s disease. A rational framework for the search of novel therapeutic approaches

Alzheimer disease (AD) is the most common cause of dementia in people over 60 years old. The molecular and cellular alterations that trigger this disease are still diffuse, one of the reasons for the delay in finding an effective treatment. In the search for new targets to search for novel therapeut...

Full description

Bibliographic Details
Main Authors: Ricardo Benjamin Maccioni, Inelia eMorales, Leonardo eGuzman-Martinez, Cristobal eCerda-Troncoso, Gonzalo Andrés Farías
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00112/full